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Elevated levels of endothelial cell-derived microparticles following short-term withdrawal of continuous positive airway pressure in patients with obstructive sleep apnea: Data from a randomized controlled trial

Abstract:

Background: Obstructive sleep apnea has been associated with impaired endothelial function; however, the mechanisms underlying this association are not completely understood. Cell-derived microparticles may provide a link between obstructive sleep apnea and endothelial dysfunction. Objectives: This randomized controlled trial aimed to examine the effect of a 2-week withdrawal of continuous positive airway pressure (CPAP) therapy on levels of circulating microparticles. Methods: Forty-one obst...

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Publisher copy:
10.1159/000342877

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Respiration
Volume:
85
Issue:
6
Pages:
478-485
Publication date:
2013-05-01
DOI:
EISSN:
1423-0356
ISSN:
0025-7931
Source identifiers:
405832
Pubs id:
pubs:405832
UUID:
uuid:c45d915c-454f-4e80-aa59-57ae59de39d5
Local pid:
pubs:405832
Deposit date:
2013-11-17

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