- Abstract:
-
The 5q- syndrome is a distinct type of myelodysplastic syndrome (MDS) characterised by refractory anaemia, morphological abnormalities of megakaryocytes, and del(5q) as the sole cytogenetic abnormality. In contrast to patients with therapy-related MDS with 5q deletions, 5q- syndrome patients have a favourable prognosis and a low rate of transformation to acute leukaemia. We have previously delineated a common deleted region of 5.6 Mb between the gene for fibroblast growth factor acidic (FGF1)...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/(sici)1098-2264(199807)22:3<251::aid-gcc11>3.0.co;2-r
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- Journal:
- Genes, chromosomes and cancer
- Volume:
- 22
- Issue:
- 3
- Pages:
- 251-256
- Publication date:
- 1998-07-05
- DOI:
- EISSN:
-
1098-2264
- ISSN:
-
1045-2257
- URN:
-
uuid:c45a049a-a824-40db-96da-18f09554df16
- Source identifiers:
-
375305
- Local pid:
- pubs:375305
- Copyright date:
- 1998
Journal article
Molecular cytogenetic delineation of the critical deleted region in the 5q- syndrome.
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