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Effect of metformin therapy on circulating amino acids in a randomized trial: the CAMERA study: Metabolism

Abstract:
Aims To investigate whether metformin therapy alters amino acid concentrations, increased levels of which have been found to predict Type 2 diabetes. Methods In the Carotid Atherosclerosis: Metformin for Insulin Resistance (CAMERA) study (NCT00723307), 173 individuals without Type 2 diabetes, but with coronary disease, were randomized to metformin (n=86) or placebo (n=87) for 18 months. Plasma samples, taken every 6 months, were analysed using quantitative n... Expand abstract
Publication status:
Accepted
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/dme.13097

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
Publisher:
Wiley Publisher's website
Journal:
Diabetic Medicine Journal website
Publication date:
2016-01-01
DOI:
ISSN:
0742-3071
Pubs id:
pubs:602507
UUID:
uuid:c44bd9f2-12d5-4868-8a8c-b6ed7bfc4538
Local pid:
pubs:602507
Source identifiers:
602507
Deposit date:
2016-02-15

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