- Abstract:
-
Rat C regions mu, gamma 1, gamma 2a, gamma 2b, gamma 2c, epsilon, and alpha have been characterized by means of chimeric antibody technology. A set of rat/mouse Ag-specific (anti-4-hydroxy-3-nitrophenacetyl) antibodies was constructed that differ only in the H chain constant region but carry identical V region and L chain, both of which are of mouse origin. All rat constant regions could be expressed and m.w. were as expected from the protein sequence. A slight variation in mobility within th...
Expand abstract - Journal:
- Journal of immunology (Baltimore, Md. : 1950)
- Volume:
- 142
- Issue:
- 9
- Pages:
- 3145-3150
- Publication date:
- 1989-05-05
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- URN:
-
uuid:c4445f8e-dd4f-4796-aca8-b2dd920f2d5f
- Source identifiers:
-
2805
- Local pid:
- pubs:2805
- Language:
- English
- Keywords:
- Copyright date:
- 1989
Journal article
A matched set of rat/mouse chimeric antibodies. Identification and biological properties of rat H chain constant regions mu, gamma 1, gamma 2a, gamma 2b, gamma 2c, epsilon, and alpha.
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