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Combined solid/solution phase synthesis of large surface area scaffolds derived from aminomethyl-benzoates.

Abstract:
A set of macrocycles was generated by solid phase synthesis of linear trimers of 5-aminoacyl-3-aminomethyl-benzoates followed by resin cleavage and solution phase macrocyclization. These scaffolds can serve as useful building blocks for molecular recognition studies, especially where differentially functionalized molecular platforms spanning large surface areas are required.
Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Journal:
Tetrahedron letters
Volume:
50
Issue:
23
Pages:
2787-2789
Publication date:
2009-06-05
DOI:
ISSN:
0040-4039
URN:
uuid:c4299747-6403-4177-91fd-a1523d55674a
Source identifiers:
117492
Local pid:
pubs:117492
Language:
English

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