Journal article
New crystal forms of Trypanosoma cruzi dUTPase.
- Abstract:
- The dUTPase from Trypanosoma cruzi has been crystallized in two crystal forms, both belonging to space group P6(3)22, with unit-cell parameters a = b = 134.67, c = 148.66 A (form I, two molecules per asymmetric unit) and a = b = 136.43, c = 68.71 A (form II, one molecule per asymmetric unit). Single-wavelength data have been collected using synchrotron radiation to 3.0 A for crystal form I and to 2.4 A for crystal form II and structure solution is under way. T. cruzi dUTPase is a potential target for anti-protozoan drug design.
- Publication status:
- Published
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- Publisher copy:
- 10.1107/s0907444901004905
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Bibliographic Details
- Journal:
- Acta crystallographica. Section D, Biological crystallography
- Volume:
- 57
- Issue:
- Pt 6
- Pages:
- 915-917
- Publication date:
- 2001-06-01
- DOI:
- EISSN:
-
1399-0047
- ISSN:
-
0907-4449
- Source identifiers:
-
31885
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:31885
- UUID:
-
uuid:c4230b91-6bda-4148-a815-de08a0beb983
- Local pid:
- pubs:31885
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2001
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