Journal article
A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart
- Abstract:
-
Elevated levels of cardiac mitochondrial uncoupling protein 3 (UCP3) and decreased cardiac efficiency (hydraulic power/oxygen consumption) with abnormal cardiac function occur in obese, diabetic mice. To determine whether cardiac mitochondrial uncoupling occurs in non-genetic obesity, we fed rats a high fat diet (55% kcal from fat) or standard laboratory chow (7% kcal from fat) for 3 weeks, after which we measured cardiac function in vivo using cine MRI, efficiency in isolated working hearts ...
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- Publisher copy:
- 10.1007/s00395-011-0156-1
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Bibliographic Details
- Journal:
- Basic Research in Cardiology
- Volume:
- 106
- Issue:
- 3
- Pages:
- 447-457
- Publication date:
- 2011-05-01
- DOI:
- EISSN:
-
1435-1803
- ISSN:
-
0300-8428
- Source identifiers:
-
149794
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:149794
- UUID:
-
uuid:c3f59c8b-f06a-408e-94b0-c14e22c7b11d
- Local pid:
- pubs:149794
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2011
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