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Pig pancreas oxygenation at 20 degrees C increases islet ATP generation but deteriorates islet function.

Abstract:

Successful pancreas preservation during storage in oxygenated perfluorodecalin (PFD) is mainly related to oxidative ATP generation during storage. Increasing the storage temperature would accelerate this process essential for resuscitation of ischemically damaged pancreatic tissue. The present study aimed at comparing islet isolation outcome from adult pig pancreata preserved in oxygenated PFD by means of a one-layer method during storage on ice or at 20 degrees C. Resected pancreata were int...

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Publisher copy:
10.3727/096368909x470838

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
Journal:
Cell transplantation
Volume:
18
Issue:
7
Pages:
745-751
Publication date:
2009-01-01
DOI:
EISSN:
1555-3892
ISSN:
0963-6897
URN:
uuid:c3f2c320-91ea-45d5-a1a0-94375e5c5b72
Source identifiers:
270669
Local pid:
pubs:270669

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