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A randomised trial of granulocyte-macrophage colony-stimulating factor for neonatal sepsis: Outcomes at 2 years

Abstract:

Objective: The authors performed a randomised trial in very preterm small-for-gestational age (SGA) babies to determine if prophylaxis with granulocyte-macrophage colony-stimulating factor (GM-CSF) improves outcomes (the PROGRAMS trial). Despite increased neutrophil counts following GM-CSF, the authors reported no significant difference in neonatal sepsis-free survival. Patients and methods: 280 babies born <31 weeks of gestation and SGA were entered into the trial. Outcome was determined ...

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Authors


Brocklehurst, P More by this author
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Journal:
Archives of Disease in Childhood: Fetal and Neonatal Edition
Volume:
98
Issue:
1
Publication date:
2013-01-05
DOI:
EISSN:
1468-2052
ISSN:
1359-2998
URN:
uuid:c3e2d654-39cf-4212-be20-0859d7b875d1
Source identifiers:
371603
Local pid:
pubs:371603
Language:
English

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