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Recognition of influenza A virus nucleoprotein by an H-2-restricted cytotoxic T-cell clone.

Abstract:
Cytotoxic T-cell clones raised against X-31 (H3N2) influenza virus in C57BL/6 mice can be directed against an influenza A virus subtype specific determinant (1). A representative T-cell clone (A3.1) has been used in combination with a set of genetically typed recombinant viruses, to show that the A/PR/8/34 nucleoprotein can be responsible for cytotoxic T-lymphocyte recognition of infected target cells.

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine
Skehel, JJ More by this author
Taylor, PM More by this author
Journal:
Virology
Volume:
133
Issue:
2
Pages:
456-459
Publication date:
1984-03-05
DOI:
EISSN:
1096-0341
ISSN:
0042-6822
URN:
uuid:c3b870c7-fe70-43e2-8246-d8bbadb86c4d
Source identifiers:
95059
Local pid:
pubs:95059

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