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Journal article

Clinical features and molecular analysis of a family with multiple colon tumours and reduced plasminogen activator activity.

Abstract:

A family is reported in which a pair of brothers has developed recurrent venous thromboses, which have been shown in one brother (the proband) to result from a reduced level of tissue plasminogen activator (t-PA) activity. Both brothers have also developed multiple synchronous and metachronous colorectal adenomas. Other pedigree members have developed colon cancers, but not multiple colonic tumours. We have shown that HNPCC and FAP/AAPC are unlikely causes of the family's phenotypes. Previous...

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Publisher copy:
10.1007/s003840050068

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Journal:
International journal of colorectal disease
Volume:
12
Issue:
1
Pages:
1-3
Publication date:
1997-01-01
DOI:
EISSN:
1432-1262
ISSN:
0179-1958
Source identifiers:
72321
Language:
English
Keywords:
Pubs id:
pubs:72321
UUID:
uuid:c3b5ba9f-e9ab-4a1f-9cc8-e736d3be572e
Local pid:
pubs:72321
Deposit date:
2012-12-19

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