Mnemonic function of the dorsolateral prefrontal cortex in conflict-induced behavioral adjustment.

Journal article

Our cognitive abilities in performing tasks are influenced by experienced competition/conflict between behavioral choices. To determine the role of the anterior cingulate cortex (ACC) and dorsolateral prefrontal cortex (DLPFC) in the conflict detection-resolution process, we conducted complementary lesion and single-cell recording studies in monkeys that were resolving a conflict between two rules. We observed conflict-induced behavioral adjustment that persisted after lesions within the ACC ...

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Authors: Mansouri, F; Buckley, M; Tanaka, K

• Publication status: Published
• Journal: Science (New York, N.Y.)
• Volume: 318
• Issue: 5852
• Pages: 987-990
• Publication date: 2007-11-01
• DOI: 10.1126/science.1146384
• EISSN: 1095-9203
• ISSN: 0036-8075
• Language: English
• Keywords: Gyrus Cinguli; Neuropsychological Tests; Electrophysiology; Prefrontal Cortex; Analysis of Variance; Memory; Behavior, Animal; Neurons; Conflict (Psychology); Reaction Time; Psychomotor Performance; Macaca; Animals; Macaca mulatta; Brain Mapping