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Discrimination of benign from malignant prostatic disease by selective measurements of single chain, intact free prostate specific antigen.

Abstract:

PURPOSE: Free prostate specific antigen (PSA) in serum consists of heterogeneous molecular subforms. Recently we developed an immunoassay for selective measurement of a subfraction of free PSA called intact PSA, which has been shown to be closely associated with prostate cancer. We assessed the ability of serum intact PSA to discriminate between benign and malignant prostatic disease. MATERIALS AND METHODS: In serum of 178 men with benign disease and 255 men with prostate cancer we measured ...

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Journal:
The Journal of urology
Volume:
168
Issue:
5
Pages:
1917-1922
Publication date:
2002-11-05
DOI:
EISSN:
1527-3792
ISSN:
0022-5347
URN:
uuid:c3999f08-3632-41ce-895b-3dfe9b015455
Source identifiers:
366021
Local pid:
pubs:366021

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