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Temporal analysis of rat growth plates: cessation of growth with age despite presence of a physis.

Abstract:

Despite the continued presence of growth plates in aged rats, longitudinal growth no longer occurs. The aims of this study were to understand the reasons for the cessation of growth. We studied the growth plates of femurs and tibiae in Wistar rats aged 62-80 weeks and compared these with the corresponding growth plates from rats aged 2-16 weeks. During skeletal growth, the heights of the plates, especially that of the hypertrophic zone, reflected the rate of bone growth. During the period of ...

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Publication status:
Published

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Publisher copy:
10.1177/002215540305100312

Authors


Oreffo, RO More by this author
Clarke, NM More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Journal:
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Volume:
51
Issue:
3
Pages:
373-383
Publication date:
2003-03-05
DOI:
EISSN:
1551-5044
ISSN:
0022-1554
URN:
uuid:c39635b1-ebc1-494a-8612-be520f8fd674
Source identifiers:
126524
Local pid:
pubs:126524

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