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Journal article

Long non-coding RNAs in B cell development and activation

Abstract:

Long noncoding RNAs (lncRNAs) are potentially important regulators of cell differentiation and development, but little is known about their roles in B-lymphocytes. Using RNA-seq and de novo transcript assembly, we identified 4516 lncRNAs expressed in 11 different stages of B cell development and activation. Most of these lncRNAs have not been previously detected, even in the closely related T cell lineage. Comparison with lncRNAs previously described in human B cells identified 185 mouse lncR...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1182/blood-2015-11-680843

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
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Publisher:
American Society of Hematology Publisher's website
Journal:
Blood Journal website
Volume:
128
Issue:
7
Pages:
e10-e19
Publication date:
2016-07-05
DOI:
EISSN:
1528-0020
ISSN:
0006-4971
URN:
uuid:c386bc96-cfce-4c87-a806-bd142af1ef1a
Source identifiers:
633435
Local pid:
pubs:633435
Paper number:
7

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