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Evidence consistent with the requirement of cresolase activity for suicide inactivation of tyrosinase.

Abstract:

Tyrosinase is a mono-oxygenase with a dinuclear copper catalytic center which is able to catalyze both the ortho-hydroxylation of monophenols (cresolase activity) and the oxidation of catechols (catecholase activity) yielding ortho-quinone products. Tyrosinases appear to have arisen early in evolution and are widespread in living organisms where they are involved in several processes, including antibiosis, adhesion of molluscs, the hardening of the exoskeleton of insects, and pigmentation. Ty...

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Publication status:
Published

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Publisher copy:
10.1620/tjem.216.231

Authors


Journal:
The Tohoku journal of experimental medicine
Volume:
216
Issue:
3
Pages:
231-238
Publication date:
2008-11-05
DOI:
EISSN:
1349-3329
ISSN:
0040-8727
URN:
uuid:c36d69c7-c3ab-466d-8b80-4acb4aac178c
Source identifiers:
132122
Local pid:
pubs:132122

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