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Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2

Abstract:

We and others have previously reported linkage to schizophrenia on chromosome 10q25-q26 but, to date, a susceptibility gene in the region has not been identified. We examined data from 3606 single-nucleotide polymorphisms (SNPs) mapping to 10q25-q26 that had been typed in a genome-wide association study (GWAS) of schizophrenia (479 UK cases/2937 controls). SNPs with P<0.01 (n=40) were genotyped in an additional 163 UK cases and those markers that remained nominally significant at P<0.01...

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Publisher copy:
10.1038/mp.2008.108

Authors


O'Donovan, MC More by this author
Williams, H More by this author
Moskvina, V More by this author
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Journal:
Molecular Psychiatry
Volume:
14
Issue:
1
Pages:
30-36
Publication date:
2009-01-25
DOI:
EISSN:
1476-5578
ISSN:
1359-4184
URN:
uuid:c356858c-6c6b-4057-890d-12652da97c1c
Source identifiers:
97641
Local pid:
pubs:97641
Language:
English
Keywords:

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