Eosinophilia and progression to active tuberculosis in HIV-1-infected Ugandans.

Journal article

It has been suggested that type 1 immune responses protect against tuberculosis (TB), while type 2 responses, such as those induced by helminths, may suppress protective responses and increase susceptibility to TB. Factors associated with progression to active TB were investigated in a cohort of HIV-1-infected Ugandan adults, a group at high risk of TB. High rates of subsequent progression to active TB were associated with eosinophil counts > or = 0.4 x 10(9)/L at enrolment. Eosinophilia a...

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Authors: Elliott, A; Kyosiimire, J; Quigley, M; Nakiyingi, J; Watera, C

• Publication status: Published
• Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene
• Volume: 97
• Issue: 4
• Pages: 477-480
• Publication date: 2003-01-01
• DOI: 10.1016/s0035-9203(03)90096-4
• EISSN: 1878-3503
• ISSN: 0035-9203
• Language: English
• Keywords: HIV-1; Adult; Tuberculosis; Schistosomiasis; Disease Progression; Female; Male; Social Class; Follow-Up Studies; HIV Infections; Humans; Eosinophilia; AIDS-Related Opportunistic Infections; Risk Factors