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Journal article

Biologics and chronic obstructive pulmonary diseases

Abstract:

The presence of airway inflammation in patients with chronic obstructive pulmonary disease (COPD) provides a rationale for biological agents targeting specific inflammatory pathways. This approach has been strikingly effective in patients with other chronic inflammatory diseases, such as rheumatoid arthritis, psoriasis, and asthma. However, there are important and unresolved challenges in COPD, including our incomplete understanding of heterogeneity of the lower airway inflammatory response a...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1016/j.jaci.2018.04.020

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Target Discovery Institute
Oxford college:
St Edmund Hall
Role:
Author
Publisher:
Elsevier Publisher's website
Journal:
Journal of Allergy and Clinical Immunology Journal website
Volume:
141
Issue:
6
Pages:
1983-1991
Publication date:
2018-05-03
Acceptance date:
2018-04-27
DOI:
EISSN:
1097-6825
ISSN:
0091-6749
Pubs id:
pubs:853191
URN:
uri:c3542887-e773-4fc3-b296-8b9c88e7f202
UUID:
uuid:c3542887-e773-4fc3-b296-8b9c88e7f202
Local pid:
pubs:853191

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