Journal article
Genome-wide association analysis identifies 27 novel loci associated with uterine leiomyomata revealing common genetic origins with endometriosis
- Abstract:
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Uterine leiomyomata (UL), also known as uterine fibroids, are the most common neoplasms of the reproductive tract and the primary cause for hysterectomy, leading to considerable impact on women's lives as well as high economic burden. Genetic epidemiologic studies indicate that heritable risk factors contribute to UL pathogenesis. Previous genome-wide association studies (GWAS) identified five loci associated with UL at genome-wide significance (P < 5 x 10-8). We conducted GWAS meta-analys...
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- Publication status:
- Not published
- Peer review status:
- Not peer reviewed
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(Pre-print, pdf, 1.3MB)
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- Publisher copy:
- 10.1101/324905
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Funding
National Institutes of Health
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Eunice Kennedy Shriver National Institute of Child Health and Human Development
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Bibliographic Details
- Journal:
- biorxiv Journal website
- Publication date:
- 2018-05-18
- DOI:
- Source identifiers:
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891021
Item Description
- Pubs id:
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pubs:891021
- UUID:
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uuid:c353f5b9-2360-4f2b-82a2-e2862ed39018
- Local pid:
- pubs:891021
- Deposit date:
- 2018-09-13
Terms of use
- Copyright holder:
- Gallagher et al
- Copyright date:
- 2018
- Notes:
- The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
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