Cholinesterase activities in cerebrospinal fluid of patients with senile dementia of Alzheimer type.

Journal article

Acetylcholinesterase (AChE) and nonspecific cholinesterase (nsChE) activities of lumbar ceresbrospinal fluid (CSF) from patients with a clinical or histological diagnosis of Alzheimer's disease have been compared with those of normal age-matched control patients and patients with dementia of non-Alzheimer aetiology. No significant differences in the AChE activity of lumbar CSF from histologically and clinically diagnosed Alzheimer's disease patients and normal age-matched controls were found,...

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Authors: Appleyard, M; Smith, A; Berman, P; Wilcock, G; Esiri, M

• Publication status: Published
• Journal: Brain : a journal of neurology
• Volume: 110 ( Pt 5)
• Issue: 5
• Pages: 1309-1322
• Publication date: 1987-10-01
• DOI: 10.1093/brain/110.5.1309
• EISSN: 1460-2156
• ISSN: 0006-8950
• Language: English
• Keywords: Humans; Butyrylcholinesterase; Acetylcholinesterase; Cholinesterases; Cerebral Ventricles; Dementia; Cholinesterase Inhibitors; Lumbosacral Region; Aged, 80 and over; Aged; Alzheimer Disease; Biopsy