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Estimating the impact of expanding treatment coverage and allocation strategies for chronic hepatitis C in a direct antiviral agent era

Abstract:

Hepatitis C virus (HCV) infection is an important worldwide public health problem, and most of the global HCV burden is in low- to middle-income countries. This study aimed to estimate the future burden of chronic hepatitis C (CHC) and the impact of public health policies using novel antiviral agents in Thailand. A mathematical model of CHC transmission dynamics was constructed to examine the disease burden over the next 20 years using different treatment strategies. We compared and evaluated...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0163095

Authors


Poovorawan, K More by this author
Pan-ngum, W More by this author
More by this author
Department:
Oxford, MSD, NDM, Tropical Medicine
Soonthornworasiri, N More by this author
Wilairatana, P More by this author
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Institute of Clinical Trials and Methodology More from this funder
Mahidol University More from this funder
National Science and Technology Development Agency of Thailand More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS One Journal website
Volume:
11
Issue:
9
Pages:
e0163095
Publication date:
2016-09-05
Acceptance date:
2016-09-07
DOI:
ISSN:
1932-6203
Pubs id:
pubs:641630
URN:
uri:c34b6402-5870-4a3c-a81a-42012dad20cf
UUID:
uuid:c34b6402-5870-4a3c-a81a-42012dad20cf
Local pid:
pubs:641630

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