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Journal article

Use of in vivo-regulated promoters to deliver antigens from attenuated Salmonella enterica var. Typhimurium.

Abstract:

This study describes the construction and analysis of three in vivo-inducible promoter expression plasmids, containing pnirB, ppagC, and pkatG, for the delivery of foreign antigens in the DeltaaroAD mutant of Salmonella enterica var. Typhimurium (hereafter referred to as S. typhimurium). The reporter genes encoding beta-galactosidase and firefly luciferase were used to assess the comparative levels of promoter activity in S. typhimurium in vitro in response to different induction stimuli and ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Role:
Author
Journal:
Infection and immunity
Volume:
67
Issue:
10
Pages:
5133-5141
Publication date:
1999-10-05
EISSN:
1098-5522
ISSN:
0019-9567
URN:
uuid:c3332705-9ac1-4f0b-918e-71ab23b65fa9
Source identifiers:
31553
Local pid:
pubs:31553

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