- Abstract:
-
Genetic variants that associate with DNA methylation at CpG sites (methylation quantitative trait loci, meQTLs) offer a potential biological mechanism of action for disease associated SNPs. We investigated whether meQTLs exist in abdominal subcutaneous adipose tissue (SAT) and if CpG methylation associates with metabolic syndrome (MetSyn) phenotypes. We profiled 27,718 genomic regions in abdominal SAT samples of 38 unrelated individuals using differential methylation hybridization (DMH) toget...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1371/journal.pone.0055923
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- Volume:
- 54
- Issue:
- 2
- Pages:
- S163-S164
- Publication date:
- 2011-09-05
- DOI:
- EISSN:
-
1932-6203
- ISSN:
-
0012-186X
- URN:
-
uuid:c30dcfdf-5922-4a0a-8994-c17131236474
- Source identifiers:
-
350726
- Local pid:
- pubs:350726
- Copyright date:
- 2011
Conference
The presence of methylation quantitative trait loci indicate a direct genetic influence on the level of methylation in adipose tissue
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