Conference icon

Conference

The presence of methylation quantitative trait loci indicate a direct genetic influence on the level of methylation in adipose tissue

Abstract:

Genetic variants that associate with DNA methylation at CpG sites (methylation quantitative trait loci, meQTLs) offer a potential biological mechanism of action for disease associated SNPs. We investigated whether meQTLs exist in abdominal subcutaneous adipose tissue (SAT) and if CpG methylation associates with metabolic syndrome (MetSyn) phenotypes. We profiled 27,718 genomic regions in abdominal SAT samples of 38 unrelated individuals using differential methylation hybridization (DMH) toget...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Statistics
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM, Biomedical Research Centre
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Role:
Author
Expand authors...
Volume:
54
Issue:
2
Pages:
S163-S164
Publication date:
2011-09-05
DOI:
EISSN:
1932-6203
ISSN:
0012-186X
URN:
uuid:c30dcfdf-5922-4a0a-8994-c17131236474
Source identifiers:
350726
Local pid:
pubs:350726

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP