Journal article icon

Journal article

Maternal SDF1 3'A polymorphism is associated with increased perinatal human immunodeficiency virus type 1 transmission.

Abstract:

Genetic polymorphisms in chemokine and chemokine receptor genes influence susceptibility to human immunodeficiency virus type 1 (HIV-1) infection and disease progression, but little is known regarding the association between these allelic variations and the ability of the host to transmit virus. In this study, we show that the maternal heterozygous SDF1 genotype (SDF1 3'A/wt) is associated with perinatal transmission of HIV-1 (risk ratio [RR], 1.8; 95% confidence interval [CI], 1.0 to 3.3) an...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Rousseau, C More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine
Rowland-Jones, S More by this author
Expand authors...
Journal:
Journal of virology
Volume:
74
Issue:
12
Pages:
5736-5739
Publication date:
2000-06-05
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
URN:
uuid:c30c3eea-3374-4f8e-ac4e-b2648686cb6a
Source identifiers:
95302
Local pid:
pubs:95302

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP