- Abstract:
-
Genetic polymorphisms in chemokine and chemokine receptor genes influence susceptibility to human immunodeficiency virus type 1 (HIV-1) infection and disease progression, but little is known regarding the association between these allelic variations and the ability of the host to transmit virus. In this study, we show that the maternal heterozygous SDF1 genotype (SDF1 3'A/wt) is associated with perinatal transmission of HIV-1 (risk ratio [RR], 1.8; 95% confidence interval [CI], 1.0 to 3.3) an...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1128/jvi.74.12.5736-5739.2000
-
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- Journal:
- Journal of virology
- Volume:
- 74
- Issue:
- 12
- Pages:
- 5736-5739
- Publication date:
- 2000-06-05
- DOI:
- EISSN:
-
1098-5514
- ISSN:
-
0022-538X
- URN:
-
uuid:c30c3eea-3374-4f8e-ac4e-b2648686cb6a
- Source identifiers:
-
95302
- Local pid:
- pubs:95302
- Language:
- English
- Keywords:
- Copyright date:
- 2000
Journal article
Maternal SDF1 3'A polymorphism is associated with increased perinatal human immunodeficiency virus type 1 transmission.
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