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Silencing cortical activity during sound-localization training impairs auditory perceptual learning

Abstract:

The brain has a remarkable capacity to adapt to changes in sensory inputs and to learn from experience. However, the neural circuits responsible for this flexible processing remain poorly understood. Using optogenetic silencing of ArchT-expressing neurons in adult ferrets, we show that within-trial activity in primary auditory cortex (A1) is required for training-dependent recovery in sound-localization accuracy following monaural deprivation. Because localization accuracy under normal-hearin...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41467-019-10770-4

Authors


Publisher:
Springer Nature
Journal:
Nature Communications More from this journal
Volume:
10
Issue:
2019
Article number:
2075
Publication date:
2019-07-12
Acceptance date:
2019-05-28
DOI:
ISSN:
2041-1723
Keywords:
Pubs id:
pubs:1004532
UUID:
uuid:c2e5baa8-39cf-4a2c-a054-645e3b35d9f1
Local pid:
pubs:1004532
Source identifiers:
1004532
Deposit date:
2019-05-31

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