BACKGROUND: Topical creams with capsaicin are used to treat pain from a wide range of chronic conditions including neuropathic pain. Following application to the skin capsaicin causes enhanced sensitivity to noxious stimuli, followed by a period with reduced sensitivity and, after repeated applications, persistent desensitisation. There is uncertainty about the efficacy and tolerability of capsaicin for treating painful chronic neuropathies. OBJECTIVES: To review the evidence from controlled ...Expand abstract
- Cochrane database of systematic reviews (Online)
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Topical capsaicin for chronic neuropathic pain in adults.
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