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A model-based approach to capture genetic variation for future association studies.

Abstract:

Genome-wide association studies are still constrained by the cost of genotyping. For this reason, the selection of a reduced set of markers or tags able to capture a significant proportion of the genetic variation is an important aspect of these studies. Most tagging SNP selection methods have been successful in capturing the genetic variation of the data from which the tags have been chosen. However, when these tags are used in an independent data set, a significant proportion of the remaini...

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Publication status:
Published

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Publisher copy:
10.1101/gr.5675406

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Institution:
University of Oxford
Department:
Oxford, MPLS, Statistics, Clinical Medicine
Role:
Author
Journal:
Genome research
Volume:
17
Issue:
1
Pages:
88-95
Publication date:
2007-01-05
DOI:
EISSN:
1549-5469
ISSN:
1088-9051
URN:
uuid:c2d2413b-c02a-4e27-a00c-6218dc6987ac
Source identifiers:
49984
Local pid:
pubs:49984

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