- Abstract:
-
In recent years, several studies have investigated the potential of immunohistochemical detection of α-synuclein in the gastrointestinal tract to diagnose Parkinson's disease (PD). Although methodological heterogeneity has hindered comparability between studies, it has become increasingly apparent that the high sensitivity and specificity reported in preliminary studies has not been sustained in subsequent large-scale studies. What constitutes pathological α-synuclein in the alimentary canal ...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Version of record
- Publisher:
- Wiley Publisher's website
- Journal:
- Movement Disorders Journal website
- Volume:
- 31
- Issue:
- 2
- Pages:
- 193-202
- Publication date:
- 2016-01-22
- Acceptance date:
- 2015-10-15
- DOI:
- EISSN:
-
1531-8257
- ISSN:
-
0885-3185
- Pubs id:
-
pubs:577774
- URN:
-
uri:c2c025fa-4d52-4ee0-ae47-fd93a9e04f36
- UUID:
-
uuid:c2c025fa-4d52-4ee0-ae47-fd93a9e04f36
- Local pid:
- pubs:577774
- Language:
- English
- Keywords:
- Copyright holder:
- Ruffmann et al.
- Copyright date:
- 2016
- Notes:
- © 2016 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Journal article
Gut feelings about α-synuclein in gastrointestinal biopsies: biomarker in the making?
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