Journal article
Strict tropism for CD71+/ CD234+ human reticulocytes limits Plasmodium cynomolgi's zoonotic potential
- Abstract:
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Two malaria parasites of Southeast Asian macaques, Plasmodium knowlesi and P. cynomolgi, can infect humans experimentally. In Malaysia, where both species are common, zoonotic knowlesi malaria has recently become dominant, and cases are recorded throughout the region. By contrast, to date only a single case of naturally acquired P. cynomolgi has been found in humans. In this study we show that whereas P. cynomolgi merozoites invade monkey red blood cells (RBCs) indiscriminately in vitro, for ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Access Document
- Files:
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(Preview, Accepted manuscript, pdf, 225.5KB, Terms of use)
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- Publisher copy:
- 10.1182/blood-2017-02-764787
Authors
Bibliographic Details
- Publisher:
- American Society of Hematology
- Journal:
- Blood More from this journal
- Volume:
- 130
- Issue:
- 11
- Pages:
- 1357-1363
- Publication date:
- 2017-07-11
- Acceptance date:
- 2017-06-30
- DOI:
- EISSN:
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1528-0020
- ISSN:
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0006-4971
- Pmid:
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28698207
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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pubs:708014
- UUID:
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uuid:c2bafd34-0e4e-4003-984d-788b916d3f2e
- Local pid:
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pubs:708014
- Source identifiers:
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708014
- Deposit date:
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2017-09-04
Terms of use
- Copyright holder:
- American Society of Hematology
- Copyright date:
- 2017
- Notes:
- Copyright © 2017 American Society of Hematology. This is the accepted manuscript version of the article. The final version is available online from American Society of Hematology at: https://doi.org/10.1182/blood-2017-02-764787
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