- Abstract:
-
Transverse aortic constriction (TAC) is used as a model of left ventricular hypertrophy and failure; however, there is extensive variability in the hypertrophic response. In 43 mice that underwent TAC with a 7-0 polypropylene suture, 13 were identified by echocardiography with initial LV hypertrophy that halted or regressed over time. Post-mortem examination on 7 of these mice found the constricting band to be intact, but partially internalized into the aortic lumen, allowing blood flow aroun...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1007/s00395-005-0546-3
-
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- Journal:
- Basic research in cardiology
- Volume:
- 101
- Issue:
- 1
- Pages:
- 8-16
- Publication date:
- 2006-01-05
- DOI:
- EISSN:
-
1435-1803
- ISSN:
-
0300-8428
- URN:
-
uuid:c2b4717a-227e-4b56-8047-5990a6f7e9b6
- Source identifiers:
-
105005
- Local pid:
- pubs:105005
- Language:
- English
- Keywords:
- Copyright date:
- 2006
Journal article
Serial high resolution 3D-MRI after aortic banding in mice: band internalization is a source of variability in the hypertrophic response.
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