Journal article icon

Journal article

Serial high resolution 3D-MRI after aortic banding in mice: band internalization is a source of variability in the hypertrophic response.

Abstract:

Transverse aortic constriction (TAC) is used as a model of left ventricular hypertrophy and failure; however, there is extensive variability in the hypertrophic response. In 43 mice that underwent TAC with a 7-0 polypropylene suture, 13 were identified by echocardiography with initial LV hypertrophy that halted or regressed over time. Post-mortem examination on 7 of these mice found the constricting band to be intact, but partially internalized into the aortic lumen, allowing blood flow aroun...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1007/s00395-005-0546-3

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Cardiovascular Medicine, BHF Centre of Research Excellence
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Cardiovascular Medicine, BHF Centre of Research Excellence
Hulbert, K More by this author
ten Hove, M More by this author
Sebag-Montefiore, LM More by this author
Expand authors...
Journal:
Basic research in cardiology
Volume:
101
Issue:
1
Pages:
8-16
Publication date:
2006-01-05
DOI:
EISSN:
1435-1803
ISSN:
0300-8428
URN:
uuid:c2b4717a-227e-4b56-8047-5990a6f7e9b6
Source identifiers:
105005
Local pid:
pubs:105005

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP