Journal article icon

Journal article

Human gamma delta T cells that inhibit the in vitro growth of the asexual blood stages of the Plasmodium falciparum parasite express cytolytic and proinflammatory molecules.

Abstract:

The functional properties, regarding parasite growth inhibition in vitro, the cytotoxic potential and cytokine profiles of human gammadelta+ and alphabeta+ T cells, T-cell lines and clones stimulated with Plasmodium falciparum-antigen-or T-cell mitogen in vitro were investigated. Using reverse transcriptase-polymerase chain reaction (RT-PCR) and specific primers, mRNA for the cytolytic molecules perforin, granzyme A and B, Fas and Fas ligand (FasL) were detected in both the gammadelta- and th...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Troye-Blomberg, M More by this author
Tangteerawatana, P More by this author
Jamshaid, R More by this author
Söderström, K More by this author
Expand authors...
Journal:
Scandinavian journal of immunology
Volume:
50
Issue:
6
Pages:
642-650
Publication date:
1999-12-05
DOI:
EISSN:
1365-3083
ISSN:
0300-9475
URN:
uuid:c2b12008-d72a-45c2-a39e-c8e2018c92f6
Source identifiers:
475978
Local pid:
pubs:475978

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP