Intra-operative deep brain stimulation of the periaqueductal grey matter modulates blood pressure and heart rate variability in humans.
INTRODUCTION: Deep brain stimulation applied to the periaqueductal grey matter (PAG) of the midbrain in humans has been shown to increase or decrease arterial blood pressure during rest and to resist the postural fall on standing. The mechanism by which this effect is elicited is unknown. We hypothesize that PAG stimulation modulates performance of the autonomic nervous system. METHODS: Five consecutive male patients of a mean age of 49.1 years underwent PAG stimulation for intractable pa...Expand abstract
- Publication status:
- Publisher copy:
- Neuromodulation : journal of the International Neuromodulation Society
- Publication date:
- Source identifiers:
- Copyright date: