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Journal article

Intra-operative deep brain stimulation of the periaqueductal grey matter modulates blood pressure and heart rate variability in humans.

Abstract:

INTRODUCTION:   Deep brain stimulation applied to the periaqueductal grey matter (PAG) of the midbrain in humans has been shown to increase or decrease arterial blood pressure during rest and to resist the postural fall on standing. The mechanism by which this effect is elicited is unknown. We hypothesize that PAG stimulation modulates performance of the autonomic nervous system. METHODS:   Five consecutive male patients of a mean age of 49.1 years underwent PAG stimulation for intractable pa...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
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Journal:
Neuromodulation : journal of the International Neuromodulation Society
Volume:
13
Issue:
3
Pages:
174-181
Publication date:
2010-07-05
DOI:
EISSN:
1525-1403
ISSN:
1094-7159
URN:
uuid:c267c21c-099f-45e9-ace0-105b41b45bf7
Source identifiers:
106870
Local pid:
pubs:106870

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