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Journal article

Donor ABCB1 variant associates with increased risk for kidney allograft failure.

Abstract:

The impact of variation within genes responsible for the disposition and metabolism of calcineurin inhibitors (CNIs) on clinical outcomes in kidney transplantation is not well understood. Furthermore, the potential influence of donor, rather than recipient, genotypes on clinical endpoints is unknown. Here, we investigated the associations between donor and recipient gene variants with outcome among 4471 white, CNI-treated kidney transplant recipients. We tested for 52 single-nucleotide polymo...

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Publication status:
Published

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Publisher copy:
10.1681/asn.2012030260

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM
Role:
Author
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Journal:
Journal of the American Society of Nephrology : JASN
Volume:
23
Issue:
11
Pages:
1891-1899
Publication date:
2012-11-05
DOI:
EISSN:
1533-3450
ISSN:
1046-6673
URN:
uuid:c242a0ef-43d2-4797-b759-69f809afc097
Source identifiers:
357868
Local pid:
pubs:357868

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