Journal article

Transcriptional repression and DNA looping associated with a novel regulatory element in the final exon of the lymphotoxin-Β gene

Abstract:: Transcriptional regulation has a critical role in the coordinate and context-specific expression of a cluster of genes encoding members of the tumour necrosis factor (TNF) superfamily found at chromosome 6p21, comprising TNF, LTA (encoding lymphotoxin-α) and LTB (encoding lymphotoxin-Β). This is important, as dysregulated expression of these genes is implicated in susceptibility to many autoimmune, inflammatory and infectious diseases. We describe here a novel regulatory element in the fourth...
Expand abstract
Collapse abstract

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Cite

Cite this record

APA Style

Wicks, K., & Knight, J. (2011). Transcriptional repression and DNA looping associated with a novel regulatory element in the final exon of the lymphotoxin-Β gene. Genes and Immunity, 12(2), 126–135.

MLA Style

Wicks, K., and J. Knight. “Transcriptional Repression and DNA Looping Associated with a Novel Regulatory Element in the Final Exon of the Lymphotoxin-Β Gene.” Genes and Immunity, vol. 12, no. 2, 2011, pp. 126–35.

Chicago Style

Wicks, K, and J Knight. 2011. “Transcriptional Repression and DNA Looping Associated with a Novel Regulatory Element in the Final Exon of the Lymphotoxin-Β Gene.” Genes and Immunity 12 (2): 126–35.
Tweet
Print

Access Document

Publisher copy:: 10.1038/gene.2010.62

Authors

+ Wicks, K More by this author

Role:

Author

+ Knight, J More by this author

Role:

Author

Bibliographic Details

Journal:: Genes and Immunity More from this journal
Volume:: 12
Issue:: 2
Pages:: 126-135
Publication date:: 2011-03-01
DOI:: 10.1038/gene.2010.62
EISSN:: 1476-5470
ISSN:: 1466-4879

Item Description

Language:: English
Keywords:: exon

DNA looping

CTCF

transcriptional regulation

LTB

TNF
Pubs id:: pubs:127410
UUID:: uuid:c2394af3-8b32-42a5-b411-6b4b256b7464
Local pid:: pubs:127410
Source identifiers:: 127410
Deposit date:: 2012-12-19

Terms of use

Copyright date:: 2011

Licence:: Terms and Conditions of Use for Oxford University Research Archive

Metrics

Views and Downloads

About views and downloads

If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP