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Journal article

Neuroimaging in amyotrophic lateral sclerosis.

Abstract:

The catastrophic system failure in amyotrophic lateral sclerosis is characterized by progressive neurodegeneration within the corticospinal tracts, brainstem nuclei and spinal cord anterior horns, with an extra-motor pathology that has overlap with frontotemporal dementia. The development of computed tomography and, even more so, MRI has brought insights into neurological disease, previously only available through post-mortem study. Although largely research-based, radionuclide imaging has co...

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Publication status:
Published

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Publisher copy:
10.2217/bmm.12.26

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neurosciences
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Journal:
Biomarkers in medicine
Volume:
6
Issue:
3
Pages:
319-337
Publication date:
2012-06-05
DOI:
EISSN:
1752-0371
ISSN:
1752-0363
URN:
uuid:c2115a8c-b07c-46cf-9f3e-39c6d21df33f
Source identifiers:
341223
Local pid:
pubs:341223

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