Journal article
HLA class I alleles tag HLA-DRB1*1501 haplotypes for differential risk in multiple sclerosis susceptibility.
- Abstract:
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The major locus for multiple sclerosis (MS) susceptibility is located within the class II region of the Major Histocompatibility Complex (MHC). HLA-DRB1 alleles, constituting the strongest MS susceptibility factors, have been widely exploited in research including construction of transgenic animal models of MS. Many studies have concluded that HLA-DRB1*15 allele itself determines MS-associated susceptibility. If this were true, haplotypes bearing this allele would confer equal risk. If HLA-DR...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Proceedings of the National Academy of Sciences of the United States of America More from this journal
- Volume:
- 105
- Issue:
- 35
- Pages:
- 13069-13074
- Publication date:
- 2008-09-01
- DOI:
- EISSN:
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1091-6490
- ISSN:
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0027-8424
Item Description
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:6120
- UUID:
-
uuid:c20ba5a5-e910-419a-a334-e97886911e88
- Local pid:
-
pubs:6120
- Source identifiers:
-
6120
- Deposit date:
-
2012-12-19
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- Copyright date:
- 2008
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