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Interleukin 7 (murine pre-B cell growth factor/lymphopoietin 1) stimulates thymocyte growth: regulation by transforming growth factor beta.

Abstract:

The effects of interleukin 7 (IL7) previously known as murine pre-B cell growth factor/lymphopoietin 1 on the growth of murine thymocytes was investigated. In the presence of a suboptimal dose of phytohemagglutinin, IL7 induced a dose-dependent increase in thymocyte proliferation which was comparable to that induced by IL1. Additionally IL7 was shown to synergize with a suboptimal dose of IL1 to enhance thymocyte proliferation. Thymocyte proliferation induced by IL7, like that induced by IL1,...

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Publication status:
Published

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Publisher copy:
10.1002/eji.1830190433

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Journal:
European journal of immunology
Volume:
19
Issue:
4
Pages:
783-786
Publication date:
1989-04-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:c1daa90b-ba1b-4732-b90f-ba910d403b21
Source identifiers:
481771
Local pid:
pubs:481771

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