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Induction of human antigen-specific and non-specific helper factors in vitro.

Abstract:

Human peripheral blood leucocytes, cultured for 4--6 days with the appropriate concentration of protein or synthetic polypeptide antigen, yield helper cells. These cells, after a further 24 hr incubation with the appropriate antigen release helper factors, which are of two types, antigen specific and non-specific; a similar situation to that described in the mouse. These factors are assayed by their effects on the plaque-forming cell response of mouse spleen cells cultures in vitro. The poten...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Journal:
Clinical and experimental immunology
Volume:
36
Issue:
1
Pages:
71-77
Publication date:
1979-04-05
EISSN:
1365-2249
ISSN:
0009-9104
URN:
uuid:c1d9b046-2dde-4f78-8e60-d9ec1233c3c1
Source identifiers:
481887
Local pid:
pubs:481887

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