Journal article
Accurate reconstruction of insertion-deletion histories by statistical phylogenetics.
- Abstract:
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The Multiple Sequence Alignment (MSA) is a computational abstraction that represents a partial summary either of indel history, or of structural similarity. Taking the former view (indel history), it is possible to use formal automata theory to generalize the phylogenetic likelihood framework for finite substitution models (Dayhoff's probability matrices and Felsenstein's pruning algorithm) to arbitrary-length sequences. In this paper, we report results of a simulation-based benchmark of seve...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 950.5KB)
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- Publisher copy:
- 10.1371/journal.pone.0034572
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Authors
Funding
National Human Genome Research Institute
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National Institutes of Health
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PloS one Journal website
- Volume:
- 7
- Issue:
- 4
- Article number:
- e34572
- Publication date:
- 2012-01-01
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
- Source identifiers:
-
325248
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:c1cd3a63-2e20-4321-b779-666a9e71b7e0
- Local pid:
- pubs:325248
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Westesson et al
- Copyright date:
- 2012
- Notes:
- Copyright 2012 Westesson et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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