Journal article
ASPP: a new family of oncogenes and tumour suppressor genes.
- Abstract:
-
The apoptosis stimulating proteins of p53 (ASPP) family consists of three members, ASPP1, ASPP2 and iASPP. They bind to proteins that are key players in controlling apoptosis (p53, Bcl-2 and RelA/p65) and cell growth (APCL, PP1). So far, the best-known function of the ASPP family members is their ability to regulate the apoptotic function of p53 and its family members, p63 and p73. Biochemical and genetic evidence has shown that ASPP1 and ASPP2 activate, whereas iASPP inhibits, the apoptotic ...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- British journal of cancer
- Volume:
- 96
- Issue:
- 2
- Pages:
- 196-200
- Publication date:
- 2007-01-01
- DOI:
- EISSN:
-
1532-1827
- ISSN:
-
0007-0920
- Source identifiers:
-
83990
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:83990
- UUID:
-
uuid:c1c6d852-5784-4edf-b3c6-0c25bf324b24
- Local pid:
- pubs:83990
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2007
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