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Journal article

Splitting the nucleus: what's wrong with the tripartite ring model?

Abstract:

The segregation of sister DNA molecules at mitosis involves their traction to opposite poles by microtubules attached to kinetochores. By creating tension required to stabilize kinetochore microtubules, sister chromatid cohesion has a key role in ensuring that sister kinetochores attach to microtubules with opposing polarity, a process known as biorientation. Cohesion is mediated by a cohesin complex whose Smc1, Smc3, and kleisin subunits form a tripartite ring thought to hold sister DNAs tog...

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Publisher copy:
10.1101/sqb.2010.75.019

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Oliveira, RA More by this author
Journal:
Cold Spring Harbor symposia on quantitative biology
Volume:
75
Issue:
0
Pages:
375-388
Publication date:
2010
DOI:
EISSN:
1943-4456
ISSN:
0091-7451
URN:
uuid:c1c3654b-ed7a-4dd0-8bcd-43cb24a6ec1a
Source identifiers:
110218
Local pid:
pubs:110218

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