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Journal article

Episodic bradycardia as neurocardiac prodrome to voltage-gated potassium channel complex/leucine-rich, glioma inactivated 1 antibody encephalitis.

Abstract:

IMPORTANCE: Voltage-gated potassium channel complex antibody (VGKCc-Ab) encephalitis is an immunotherapy-responsive syndrome usually associated with causative antibodies that target the leucine-rich, glioma inactivated 1 (LGI1) protein. Although it is expressed throughout the brain, LGI1 is not known to be expressed in cardiac tissue. We describe a novel neurocardiac prodrome of VGKCc-Ab/LGI1-encephalitis. OBSERVATIONS: Among 14 patients with VGKCc/LGI1-Ab encephalitis evaluated in the Univer...

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Publication status:
Published

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Authors


Bettcher, BM More by this author
Geschwind, MD More by this author
Gelfand, JM More by this author
Journal:
JAMA neurology
Volume:
71
Issue:
10
Pages:
1300-1304
Publication date:
2014-10-05
DOI:
EISSN:
2168-6157
ISSN:
2168-6149
URN:
uuid:c1bd052e-943a-42f1-8813-7926ba70a451
Source identifiers:
482553
Local pid:
pubs:482553

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