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Journal article

Effect of irradiation and bone marrow transplantation on angiotensin II-induced aortic inflammation in ApoE knockout mice

Abstract:

Background and aims

Angiotensin II (Ang II) infusion promotes the development of aortic aneurysms and accelerates atherosclerosis in ApoE-/- mice. In order to elucidate the role of hematopoietic cells in these pathologies, irradiation and bone marrow transplantation (BMT) are commonly utilized. The aim of this study was to investigate the effects of irradiation and BMT on abdominal and thoracic aortic aneurysm formation and acute leukocyte recruitment in the aortic root and desce...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM; RDM Cardiovascular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM; RDM Cardiovascular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM; RDM Cardiovascular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM; RDM Cardiovascular Medicine
Role:
Author
National Institute for Health Research More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Atherosclerosis Journal website
Publication date:
2018-07-23
Acceptance date:
2018-07-12
DOI:
EISSN:
1879-1484
ISSN:
0021-9150
Pubs id:
pubs:890960
URN:
uri:c1b9e81b-2016-433e-8839-afbf846be116
UUID:
uuid:c1b9e81b-2016-433e-8839-afbf846be116
Local pid:
pubs:890960

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