Journal article icon

Journal article

Multilayered defense in HLA-B51-associated HIV viral control.

Abstract:

Polymorphism in the HLA region of a chromosome is the major source of host genetic variability in HIV-1 outcome, but there is limited understanding of the mechanisms underlying the beneficial effect of protective class I alleles such as HLA-B57, -B27, and -B51. Taking advantage of a unique cohort infected with clade B' HIV-1 through contaminated blood, in which many variables such as the length of infection, the infecting viral strain, and host genetic background are controlled, we performed ...

Expand abstract

Actions


Access Document


Publisher copy:
10.4049/jimmunol.1100316

Authors


Expand authors...
Journal:
Journal of immunology (Baltimore, Md. : 1950)
Volume:
187
Issue:
2
Pages:
684-691
Publication date:
2011-07-05
DOI:
EISSN:
1550-6606
ISSN:
0022-1767
URN:
uuid:c1b42cca-d45f-4daf-86fb-12a25a09fb47
Source identifiers:
176647
Local pid:
pubs:176647

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP