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Journal article

Benefits of a pharmacology antimalarial reference standard and proficiency testing program provided by the Worldwide Antimalarial Resistance Network (WWARN).

Abstract:

Comprehensive assessment of antimalarial drug resistance should include measurements of antimalarial blood or plasma concentrations in clinical trials and in individual assessments of treatment failure so that true resistance can be differentiated from inadequate drug exposure. Pharmacometric modeling is necessary to assess pharmacokinetic-pharmacodynamic relationships in different populations to optimize dosing. To accomplish both effectively and to allow comparison of data from different la...

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Publication status:
Published

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Publisher copy:
10.1128/aac.02362-14

Authors


Lourens, C More by this author
Lindegardh, N More by this author
Barnes, KI More by this author
Guerin, PJ More by this author
Sibley, CH More by this author
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Publisher:
American Society for Microbiology
Journal:
Antimicrobial agents and chemotherapy
Volume:
58
Issue:
7
Pages:
3889-3894
Publication date:
2014-07-05
DOI:
EISSN:
1098-6596
ISSN:
0066-4804
URN:
uuid:c1a5fa83-2f38-40ea-984b-0e5585b3ed30
Source identifiers:
463386
Local pid:
pubs:463386
Language:
English

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