- Abstract:
-
Background
Given the risk of artemisinin resistance spreading from the Greater Mekong sub-region, prospective monitoring in sub-Saharan Africa should be expedited. Molecular biology techniques used for monitoring rely on the detection of k13 validated mutants by using PCR and Sanger sequencing approach, usually not available in malaria endemic areas.
Methods
A semi-automated workflow based on the easyMAG® platform and the Argene Solution® (bioMérieux, Marcy l’Etoi...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Publisher:
- BioMed Central Publisher's website
- Journal:
- Malaria Journal Journal website
- Volume:
- 17
- Issue:
- 1
- Pages:
- 175
- Publication date:
- 2018-04-24
- Acceptance date:
- 2018-04-18
- DOI:
- EISSN:
-
1475-2875
- Pubs id:
-
pubs:846037
- URN:
-
uri:c182d71d-defe-40c1-984a-752c1365cc40
- UUID:
-
uuid:c182d71d-defe-40c1-984a-752c1365cc40
- Local pid:
- pubs:846037
- Language:
- English
- Keywords:
- Copyright holder:
- Dhorda et al
- Copyright date:
- 2018
- Notes:
- © The Author(s) 2018. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Journal article
A novel field-based molecular assay to detect validated artemisinin-resistant k13 mutants
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Funding
Wellcome Trust
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bioMérieux
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Institute Pasteur Paris
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