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Journal article

NF-κB as a target for modulating inflammatory responses.

Abstract:

The inflammatory response is of major importance in host defence, but is involved in all acute and chronic diseases. Multiple inflammatory cells and molecules are involved. Among the latter, the Nuclear Factor -κB (NF-κB) has been found to be most important and present in all cell types. NF-B regulates the expression of a large number of genes involved in inflammation. NF-κB plays a key role in the orchestration of the multifaceted inflammatory response, not only in the first pro-inflammatory...

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Publication status:
Published

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Publisher copy:
10.2174/138161212803530763

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Journal:
Current pharmaceutical design
Volume:
18
Issue:
35
Pages:
5735-5745
Publication date:
2012-01-01
DOI:
EISSN:
1873-4286
ISSN:
1381-6128
URN:
uuid:c181acc1-4c2e-4b95-9241-45dbf91f66cb
Source identifiers:
366464
Local pid:
pubs:366464

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