Journal article icon

Journal article

Virological synapse-mediated spread of human immunodeficiency virus type 1 between T cells is sensitive to entry inhibition.

Abstract:

Human immunodeficiency virus type 1 (HIV-1) can disseminate between CD4(+) T cells via diffusion-limited cell-free viral spread or by directed cell-cell transfer using virally induced structures termed virological synapses. Although T-cell virological synapses have been well characterized, it is unclear whether this mode of viral spread is susceptible to inhibition by neutralizing antibodies and entry inhibitors. We show here that both cell-cell and cell-free viral spread are equivalently sen...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1128/jvi.02651-09

Authors


Briggs, JA More by this author
Expand authors...
Journal:
Journal of virology
Volume:
84
Issue:
7
Pages:
3516-3527
Publication date:
2010-04-05
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
URN:
uuid:c15fd23b-779c-40c0-9af8-58c0a6d03e79
Source identifiers:
46164
Local pid:
pubs:46164

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP