Journal article
Normal in vivo skeletal muscle oxidative metabolism in sporadic inclusion body myositis assessed by 31P-magnetic resonance spectroscopy.
- Abstract:
-
Sporadic inclusion body myositis (s-IBM) is a chronic inflammatory myopathy of unknown pathogenesis. The common findings of ragged red fibres, cytochrome c oxidase-negative fibres and multiple mitochondrial DNA deletions in the muscle of patients with s-IBM have suggested that a deficit of energy metabolism may be of pathogenic relevance. To test this hypothesis we used 31P magnetic resonance spectroscopy to assess in vivo skeletal muscle mitochondrial function in the calf muscles of 12 patie...
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Bibliographic Details
- Journal:
- Brain : a journal of neurology
- Volume:
- 121 ( Pt 11)
- Issue:
- 11
- Pages:
- 2119-2126
- Publication date:
- 1998-11-01
- DOI:
- EISSN:
-
1460-2156
- ISSN:
-
0006-8950
- Source identifiers:
-
248136
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:248136
- UUID:
-
uuid:c153b7c9-09f4-46fc-89fd-9c850e0582bc
- Local pid:
- pubs:248136
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 1998
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